Comprehensive Chemical Exposure Framework

Title Page

1.0 Introduction

2.0 Literature Review

3.0 Model Framework

4.0 Scenarios
4.1 Life Stages
4.2 Scenario 1
    Model Flow Diagram 1
4.3 Scenario 2
    Model Flow Diagram 2
4.4 Scenario 3
    Model Flow Diagram 3
4.5 Scenario 4
    Model Flow Diagram 4
4.6 Process Flow
4.7 Gap Analysis

5.0 Qualitative Analysis

6.0 Recommendations

7.0 References

Appendix A

4.5 Scenario 4


Figure 4.5.1  Life Stages For Exposure Scenario 4


Scenario 1
Scenario 2
Scenario 3
Scenario 4

Scenario 4

This section provides the conceptual model for the exposure pathways associated with Exposure Scenario 4. The conceptual model and associated assumptions are critical in determining the type of the models, algorithms, and databases required to satisfy the needs of the modeling scenario. Figure 4.5.2 provides an illustration of the conceptual model for Exposure Scenario 4.

Residential Outdoor Description
- 1-story Townhouse in MA with small grass lawn and shrubbery

Smoking Description
- Smokes 15-20 cigarettes per day since age 18
- Assume man smokes indoors and outdoors at home

Exposure at Home to SVOC Compound Groups A & B (Scenario 1)

Exposure at Home and in Car to VOC Compound Group E
- Compound Group E: MTBE in gasoline
- Exposure during car repair (4 times/yr)
- Exposure during lawn mowing (20 times/yr), lawn trimming (20 times/yr), and shrubbery trimming (4 times/yr)
- Exposure during auto fueling (52 times/yr) & driving (1 hr/day)
- Background exposure indoors

Scenario 4 Picture

Figure 4.5.2  Illustration Depicting The Setting For Exposure Scenario 4 In Study

Assumptions about Working Conditions, Home Conditions, Exposures & Activities
- Workplace exposures unknown so considered negligible and part of background
- No protective gear when working on car, lawnmower, and other at-home jobs
- Paints the home interior every 5 years
- Exterior is brick so no painting needed

Adult Age Timeline
- Working
- - Adult (25-35 years)
- - Middle Adult (35-50 years)
- - Senior Adult (50-65 years)
- Senescence (65-75 years)


Adult Age Timeline
- Health effects will be calculated for the adult from 25 years of age through retirement. Depending on model outputs, this can be a cumulative time distribution or a time-weighted value.
---- Exposure during car repair (4 times/yr); assume no protective gear
---- Exposure during lawn mowing (20 times/yr), lawn trimming (20 times/yr), and shrubbery trimming (4 times/yr)
---- Exposure during auto fueling (52 times/yr) & driving (1 hr/day)

Figure 4.5.3  CCEF Model Flow Diagram Scenario 4